Antiepileptic Drug Interactions: A Clinical Guide, Third Edition
Springer | Neurology | August 27, 2016 | ISBN-10: 3319329081 | 340 pages | pdf | 7.8 mb
Authors: Patsalos, Philip N
Covers all clinically licensed AEDs, including those licensed only in specific countries or that have limited indications
Highlights the way AED interactions occur in three separate sections
Includes details of the mechanism and magnitude of the interaction between drugs
Both pharmacokinetic and pharmacodynamic interactions are described
Includes AED combinations that are not associated with interactions
Now includes sections on recently licensed AEDs perampanel and brivaracetam
This updated third edition of a successful book is a description of both pharmacokinetic and pharmacodynamic antiepileptic drug (AED) interactions, including details of the magnitude and mechanism of interactions, and also of drug combinations that are not associated with interactions and therefore can be coprescribed without undue concern. Presented in alphabetical order and by drug class, drug interactions that occur between AEDs and also between AEDs and non-AEDs are described in three sections: Drug interactions between AEDs; Drug interactions between AEDs and non-AED Drugs: Interactions affecting AEDs; Drug interactions between AEDs and non-AED Drugs: Interactions affected by AEDs.
Antiepileptic Drug Interactions: A Clinical Guide, 3rd Edition with its clear, concise and unambiguous content will
allow physicians and allied health professionals to make more rational choices when AED polytherapy regimens are indicated. There is always a choice and avoiding highly interacting drugs and choosing drug combinations that are minimally interacting or do not interact should be the goal in treating patients with epilepsy. This book provides all the necessary information so as to allow this goal to be achieved and, if necessary, to aid effective management of AED interactions.
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