I use Prinect PDF Toolbox 16 and the Qualify sequence in the Prinect Workflow if you have it.
For me and my team,
we use Quite Impossing, it's all in one tool if you need to split, combine, add trim mark, step and repeat, add comment, trim and shift, etc.
try this tool, you'll see the power!
I use Quite Impossing. But ATTENTION remover Bleed in file before split.
Quite Imposing ... all life long
for simple splitting spreads
the click and go interface of pitstop is the fastest
Most times we are using callas df toolbox, since it has nice functions to split/merge pdf files.
Either Acrobat Pro or Pitstop Pro; I haven't yet found a PDF problem I couldn't solve with these tools...
Quite imposing seems to do this perfectly.
But as people have pointed out, you need to be mindful of the bleed.
I generally use QI with PitstopPro.
Once a page is split in two, I use PitstopPro to extend out the bleed.
I use Quite Impossing